Amla has a long tradition in being used for improving the health of hair and scalp. It is widely used in hair care preparations as a natural hair conditioner.
The most commonly implicated androgen in hair loss is dihydrotestosterone (DHT), which is a very potent form of testosterone. It is generated in the body by the conversion of testosterone by the enzyme 5-α reductase. It stands to reason that if we could decrease the amount of this enzyme, 5-α reductase, in the blood or in the hair follicles, less testosterone would be converted to DHT, and therefore DHT levels would be lower. Inhibitors of 5-α reductase thus help in hair fall management.
Saberry® was found to exhibit 5-α reductase inhibitory activity (about 80% inhibition at a concentration of 250 µg/ml), validating its potential applications in hair care products.
Dosage form and suggested use level
Saberry®® was found to exhibit 5-α reductase inhibitory activity (about 80% inhibition at a concentration of 250 µg/ml), validating its potential applications in hair care products.
Saberry® be used at levels of 0.2% to 1.0% w/w in topical formulations.